Welcome to Shirleys Ice Cream | Coffee | Sandwich Shop! After you check out our website we invite you to come on in and chill out with the best Ice Cream and Specialty Treats, Sandwiches, Soups and Salads, and Specialty Espresso and Coffee Drinks available in the Florida Keys. Shirleys is located in the Big Pine Shopping Plaza on Big Pine Key. We are Open EVERY DAY from 9:00am till 9:00pm. We look forward to seeing you soon!